When the plague epidemic devastated Europe in the 14th century, a rule was introduced in Venice,
according to which arriving ships had to anchor for 40 days before the crew and passengers were allowed to land. This practice was called "quarantino" - a derivative of the Italian "forty", hence the word "quarantine".
Quarantine was introduced in 1348 by the Venetian Doge Andrea Dandolo. All the infected were sent to the island of Lazaretto, where they lived out their last days, since there was no cure for the plague. The quarantine in Venice worked, and looking at Venice, other European rulers began to introduce quarantine measures in their cities.
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