CreationPreludeInGen's chief scientist, Dr. Henry Wu, was fascinated with the possibility to create entirely new species by gene mixing, ever since he learned that the inclusion of frog DNA had given the dinosaurs the ability to switch gender. On May 21, 1997, he created Karacosis wutansis, a hybrid plant. On April 5, 2009, another hybrid was created.
Indominus rex on the Hammond Creation Lab computer.
Years after opening, Jurassic World's success was lower in 2011 unlike the previous years of its operation. Simon Masrani attended a meeting on April 4, 2012, in which the board of his company unanimously desired a new attraction for Jurassic World to satisfy investors. After he had gotten out of the meeting, Simon emailed Dr. Henry Wu his approval to create a new species. The result was a genetically modified hybrid of several dinosaur genera and modern animals. Development of the hybrid began in 2012 in the Hammond Creation Lab sometime after the board meeting. Unknown to Masrani was that Dr. Henry Wu, the creator of the hybrid, had made a deal with InGen Security Division commander Vic Hoskins to weaponize it in a grand scheme to have dinosaurs be used in military operations and kept many of the creatures used in its creation a secret. Upon Simon Masrani's announcement of the creation of the genetic hybrid, now named Indominus rex, online ticket sales for Jurassic World skyrocketed.